027/22

29.

30.

31.

32.

33.

34.

Which of the deficiency leads to Wiskott-Aldrich syndrome ?
A) T and B cell B) T cell ©) 8 ‏الوه‎ D) Complement

Which of the following statement/statements is/are true of tumour antigens ?

i. Oncofetal antigens are found in embryonic and malignant cells.

ii. Carcinoembryonic antigen can be detected in the serum of patients with colon of
carcinoma.

iii. The tumour associated transplantation antigens of virus induced tumours is virus
specific.

iv. The tumour antigens are absent in the corresponding normal cells of the host.

A) i, ii and iii 8) i and ii C) ii and iii D) Only iv

O-linked oligosaccharides are added to the serine or threonine residues of proteins
post-translationally in the Golgi apparatus while N-linked oligosaccharides are added
cotranslationally to the asparagine residues of proteins in the endoplasmic reticulum.
Which one of them can influence the folding of the protein the most ?

A) O-linked oligosaccharides

B) N-linked oligosaccharides

C) Both O-linked and N-linked oligosaccharides show equal influence

D) Both O-linked and N-linked oligosaccharides cannot influence

Of the following lipid components, which one increases the fluidity of the cell membrane
the most ?

A) Cis unsaturated fatty acids B) Trans unsaturated fatty acids

C) Long chain saturated fatty acids D) Medium chain saturated fatty acids

When a protein denatures

A) Primary, secondary and tertiary structures are altered and its function is lost

B) Secondary and tertiary structure are altered, but primary structure and its functions

are retained

C) Secondary and tertiary structure are altered, but primary structure is intact, though

its function is lost

D) Primary, secondary and tertiary structures is intact, but loses its function because
of the changes in quaternary structure

A researcher prepared a plant extract which when added to the enzyme pepsin, the
enzyme activity reduced to 2/3" of its original activity. When double the amount of
protein substrate was added to the mixture, the enzyme activity came back to the original
level. What would be the maximum reaction velocity observed in the presence of the
plant extract ? (Maximum reaction velocity in the absence of the extract is designated

as Vinax) 9 9
max ©) 2k Vinax D) 14 Vinax