B:-Oncogenic effect is due to gain of function of a protein that stimulates cell growth and proliferation
C:-Mutations in oncogenes may be present in somatic or germ cells
D:-Usually do not show tissue preference with respect to the type of cancers in which they are found
Correct Answer:- Option-C
Question39:-All the following are multienzyme complexes EXCEPT
A:-Pyruvate carboxylase
B:-Alpha keto dehydrogenase
C:-Acetyl Co A carboxylase
D:-Pyruvate kinase
Correct Answer:- Option-D
Question40:-Which of the following is an example for non-competitive inhibition?
A:-Allopurinol inhibits xanthine oxidase
-Fluoride inhibits enolase
-fluorouracil inhibits thymidylate synthase
D:-Lovastatin inhibits HMG Co A reductase
Correct Answer:- Option-B
Question41:-Which of the following is NOT a serine protease?
A:-Trypsin
-Thrombin
C:-Carbonic anhydrase
D:-Chymotrypsin
Correct Answer:- Option-C
Question42:-Which is the best marker of ventricular dysfunction?
A:-CK-MB
-Cardiac troponin |
C:-Brain natriuretic peptide
D:-Myoglobin
Correct Answer:- Option-C
Question43:-Select the glucose transporter that is insulin dependent.
A:-GLUT 2
B:-GLUT 4
C:-GLUT 5
D:-SGLT 1
Correct Answer:- Option-B
Question44:-Which of the following statement is FALSE regarding mitochondrial DNA?
A:-Majority of the mitochondrial proteins are coded by mitochondrial DNA
B:-Mitochondrial DNA have high mutation rate than nuclear DNA
C:-Mitochondrial cytopathies show a maternal non-mendelian inheritance
D:-Mitochondrial DNA shows heteroplasmy
Correct Answer:- Option-A
Question45:-Regarding p53 all the statements are true EXCEPT
A:-Is a DNA binding transcription factor
B:-Induces the genes that induce apoptosis
C:-Is the least mutated genes in human cancers
D:-Is a tumor suppressor gene
Correct Answer:- Option-C
Question46:-Regarding apoptosis, select the FALSE statement.
A:-Cytochrome c is an inducer of apoptosis
B:-bcl-2 is an apoptosis protecting gene
C:-Caspase 3 is the initiator caspase of apoptosis
D:-Ceramide is an important regulator of apoptosis
Correct Answer:- Option-C
Question47:-Which one of the following is a chain breaking anti-oxidant?
A:-Catalase
B:-Vitamin E
C:-Glutathione peroxidase
D:-Ethylenediaminetetraacetate
Correct Answer:- Option-B
Question48:-Select the enzyme that is NOT present in the liver.

Cy