42. A high ratio of insulin to glucagon can :
(A) Promote glvcogenolysis (8) Found in Type 1 Diabetes Mellitus
(€) Occurs during fasting state (D) Prometes synthesis വ്‌ Glycogen

43. The ATP/AMP ratio has a major effect upon the rate of ATP production by glycolysis.
ATP and AMT bind to allosteric sites on :

(வ) Hexokinase (18) Glucokinase
(2) Phosphofructokinase-1 (11) Phosphofructokinase-2

44. The function of an adjuvant in a vaccine is :
(A) Distribution (8) Absorption (C) Antigenicity (D) Metabolism

45. Which of the following statements about dietary fiber is/are correct ?
(ക) റിയാ! fiber increases stool bulk and decreases transit time
(8) Water-soluble fiber helps to lower serum cholesterol in most people
(€) Mucilaginous fiber slows the rate of digestion and absorption of carbohydrate
(D) All of the above

46. Creatine kinase is an :
(A) Transferase {B) Lyase (C) Hydrolase (D) - Isomerase

47. Cholesterol inhibits estrogen action through its influence on :
(ക) ೧೩88 (ए) ட (ಲ) ೧೫೫1 (1) E-RAF

48. ಟಿ೧೮ 0೪ 01 the following enzymes can utilize both NAD* and NADP* as a coenzyme :
(ക) Aldehyde dehydrogenase (8) Alcohol dehydrogenase
(€) Glutamate dehydrogenase (9) Glycerol-3-P dehydrogenase

49. Excretion of conjugated bilirubin from liver cells into biliary canaliculi is defective in :
(A) Gilbert's disease (B) Crigler-Najjar syndrome
(<) Lucey-Driscoll syndrome (D) Rotor’s syndrome

50. Which signalling sequence uses both hydrocarbon and jons as second messengers ?
(ക) PKC activation of RNA polymerase
(8) Ras activation of MSK1
(त) Cyclin D/CDK, activation of E,F
(D) RTK activation of MAP kinase

189/2015 8 A