PROVISIONAL ANSWER KEY

Question Paper 6०८९; 18/2022/0L

Category Code: 344/2021

Exam: Assistant Professor in Rasasasthra and Bhaishajyakalpana
Date of Test 32-03-2022

Department ‘Ayurveda Medical Education

Alphacode A

Question1:-The inflammatory response of corticosteroids are better explained by their binding to nuclear transcription factors in the cell cytosol, which further translocate into the
nucleus and subsequently inhibits transcription of DNA to mRNA affecting concemed proteins. This statement better explains

‘Ac Dose-response relationship
B:-Pharmacodynamics
C:Pharmacokineties
D:-Therapeutic index

Correct Answer: Option ®

‘Question2:-Find out the correct statement/statements
1. Pharmaceutical equivalents have different active moieties with the same dose and similar
therapeutic effects,
1. Iftwo drug products produce same therapeutic effects when they are therapeutic
equivalents.
11. Pharmaceutical altematives always must have the same amount of the same active
moiety.
IV, Two drug products are bioequivalent if they are pharmaceutical alternatives or
pharmaceutical equivalents with similar bioavailability under the same molar
concentrations,

Acland ॥
Bell and lV
0
De land 1v

Correct Answer: 8
Question3:-Find out the correct statement/statements regarding Adverse Drug Reactions (ADR)
‘An exaggerated effect of a drug used in normal doses can be an ADR.

॥. Allergic reactions that are not dose related but occurs to ३ pre-exposed drug (sensitized)
can be an ADR.

11. Unexpected effects of a drug that are often very serious occurring in a small number of
people arising due to genetic or metabolic dferences relating to that drug metabolism.
‘Acland ॥ are correct
8:1 and Ill are correct
Only ॥ 15 correct
പിഡി correct
Correct Answer:- Option-D
Questioné:-All are examples of plausible herb-drug interaction except
‘AcAllium sativum with warfarin showing increased bleeding
Bs-Increased plasma concentration of the drug rifampicin in pulmonary tuberculosis in the presence of Piper longum and Piper nigrum
Possible potentiation of oral and topical corticosteroids by Glycyrthiza glabra
न absorption of orally administered drugs after Cassia senna intake
Correct Answer:- Option-D
Questions:-The incorrect statement among the following is
‘A-Call lines most often offer consistent samples with reproducible results
B:-Use of immortalized human cell lines always need ethical clearance
Cell lines can be useful tools for vaccine and antibody production
D:-Primary cells are difficult to maintain than cell ines,
Correct Answer: Option ®
Question6:-About 10 to 20 mg of this element is present in human body, of which 25 to 40% is in bones. Brain, kidney, liver ad pancreas also contain this element. It is available as a
dietary supplement, and is a cofactor to many enzymes crucial for reactive oxygen species scavenging. It also helps in immune response and aid in cholesteral, amino acid and

carbohydrate metabolism. Although toxicity from excess dietary intake has not been reported so far, high level occupational exposure and related toxicity can cause neurological

symptoms like tremors, hearing loss, muscle spasm etc. It may also cause mania, depression, delusions, head ache and lower extremity weakness. The element described here best
Suits to

കിസ

छरा