D:-South western blot

Correct Answer: 8

‘Question89:-In cancer patients who have been continuously receiving methotrexate, the target cells of tumor with time become sensitive to his drug. In this case, most commonly
gene amplification of the following enzyme is observed:

‘Ac Dihydrofolate reductase
B:-Thiaminase
C-Deaminase
D:-Thioredoxin reductase

Correct Answer: Option:

Question90:-A doctor administered allopurinol to a 26-year old young man with symptoms of gout. Which of the following pharmacological action of allopurinol ensures therapeutic
effect?

Acinhibiting uric acid synthesis
B-Increasing uric acid excretion

ಟಟ leucocyte migration in the joints
D:-General ant-inflammatory effect

Correct Answer: Option:

वा 56-year old man was operated on prostate cancer, three months later he underwent a course of radiotherapy and chemotherapy. .The complex of medicinal
preparations prescribed to the patient included 5-fluoro-deoxyuridine, which is a thymidylate synthase inhibitor, Which of the following biomolecule's synthesis is blocked by the drug?

ക
नि
(व
ರಿ:

Correct Answer: 00६०५

‘Question92:-A patient with radiation therapy because of brain tumor was prescribed vitamin ह and a micro element with antioxidant function. Which of the following can be used for
this purpose?

Ac Fluorine
B:-Selenium
பளு
പിനെ

Correct Answer: 8

Question93:-A 3-year old child comes to the hospital with history of biting his lips and fingers, involuntary movements of upper limb and mental retardation. he has > younger healthy
sister. Lab investigations showed high serum uric acid. Which of the following is the most likely diagnosis?

AcAdenine deaminase
B:-LeschNyhah Syndrome
೦೫೫೫೦ aciduria
D-Fragile X syndrome

Correct Answer: 8

Question94:-A 7-year boy comes to the hospital with yellow discoloration of eyes, decreased apetite and general malaise for last 1 week. She has been passing dark colored urine and
high colored faces for the same duration. Lab investigations showed serum total bilirubin 4.5 mg%, direct bilirubin 1.2 mg%, indirect faeces 3.3 mg%. liver enzymes are normal. Which
of the following is the most likely cause of jaundiced in this patient?

A: Obtrusive jaundice
B:-Physiological jaundice
C:-Hepatic jaundice
D:-Hemolytic jaundice

Correct Answer: Option-D

Question95:-A 20-year old male visits dermatology OPD with complaints of increased sensitivity to sunlight causing blistering and crusting of skin only few minutes of sun exposure.
Delayed growth and intellectual disability were noticed. Skin biopsy was taken. Which of the following is the most likely diagnosis?

‘A: Xeroderma pigmentosum
B:-Pellagra

Vitamin A deficiency
D:-Zine deficiency

Correct Answer: Option:

‘Question96:-a 20-year old male patient presented with severe abdominal pain with difficulty in fine motor tasks. Lab investigation showed elevated liver enzymes and increased
urinary calcium and phosphate Opthalamolagical examination revealed Kayser Fleischer ring in the cornea. Which of the following is most likely cause of the presenting symptoms in

this case?