FINAL ANSWER KEY

Question Paper 0०९; 7/2021/0L
Category Code: 010/2020.

Exam: Assistant Professor in Obstetrics and Gynaecology
Date of Test 15.03.2021

Department Medical Education Services

Alphacode A

Question1:-All are TRUE regarding Fetomatemmal unit in pregnancy EXCEPT
As-Progesterane production by the placenta is largely independent of the quantity of precursor available, the utero-placental perfusion and fetal well-being
BeThere is 2 17 alpha hydroxylase enzyme biock in the fetus and placenta has very little 3 beta hydroxyl steroid dehydrogenase activity
CCholesteral and pregnenolone are obtained mainly from the maternal bloodstream for placental progesterone synthesis
D:-In human syncytiatrophoblast, estradiol increases progesterone production by means of an increase in LDL uptake
Correct Answer: 8
Question2:-All are TRUE statements about Corpus luteum of Pregnancy EXCEPT
Ac-Progesterone is largely produced by the corpus luteum until about 10 weeks of gestation
B= Pulsatile luteinizing hormone (LH) and human chorionic gonadotropin (hCG) from the implanting pregnancy stimulate progesterone production by the corpus luteum,
Cain the luteal phase of conception cycles, progesterone concentrations increase from about 1-2 mg/mL on the day of the LH surge to a plateau of approximately 10-35 mg/mL
ഉംം transitional luteo-placental shift takes place between the 10" week and 12" week
Correct Answer: Option-D
Question3:ಸಿ maximal level of about 100,000 IU/L in the maternal circulation is reached at 8-10 weeks of gestation
Be-Long halflife of hCG (48 hours) is due mainly to the greater amino acid content of beta subunit
CHyperglycosylated hCG is the major circulating form of hCG regulating trophoblastic invasion in the first weeks of normal pregnancies
D:-B-hCG can be detected in maternal blood about the eighth day after ovulation or one day after implantation
Correct Answer: 8
‘Question4:-Find out the FALSE statement regarding human parturition
കുന്നം initiating step in the sequence of events leading to parturition could bean increase in fetal ACTH and cortisol secretion and an increase in placental CRH
BeThere is a definite decline in peripheral blood levels of progesterone prior to parturition and not just ३ functional withdrawal
ಲಗ increase in estrogen levels in matemal blood begins at 34-35 weeks

D:-The activity of 15-hydroxyprostaglandin dehydrogenase decreases in the myometrium and the chorion during labor and causes increase in prostaglandins associated with
parturition

Correct Answer: Option ®
QuestionS:-All the following statements about fetal lung surfactant are TRUE EXCEPT
‘As Phosphatidyicholine (lecithin) and phosphatidylglycerol (PG) are present in only small concentrations until the last 5 weeks of pregnancy
B:-At 20-22 weeks of pregnancy, a less stable and less active lecithin, palmitoyl-myristoyl lecithin is formed
ಲಯ about the 30" week of gestation, there is a sudden surge of dipalmitoyl lecithin, the major surfactant lecithin

ഉംം Sphingomyelin concentration of amniotic fluid changes relatively little throughout pregnancy and prior to 34 weeks, the Lecithin : Sphingomyelin L/S ratio is approximately
1:1

Correct ‏ب مومه‎ Option-C
(०५८०४०१6. ५॥ the following are TRUE statement about gonadal differentiation EXCEPT
‘Act now appears that both testis and ovary differentiation require dominantly acting genes
B:-SRY activation of SOX 9 may be all that is necessary to activate other genes important to testis development
C-WNTA and R-Spondin 1(RSPO1) genes team to promote ovary development via repression of SOX9

D:-Ovarian differentiation is considered the “default” pathway of sexdetermination the automatic result in the absence of a testis-determining factor

Correct Answer: Option-D
Question7:-All are TRUE statements about Complete Androgen insensitivity EXCEPT
‘A-One in three phenotypic sisters of an affected individual may have an XY karyotype but 40% may not have a family history

ഉണട normal testes produce normal amounts of AMH and testosterone and absent spermatogenesis, serum LH levels are increased and the serum FSH usually is in the normal
range

பொறவு present with primary amenorthea, normal breast development, absent or scant pubic and axillary hair, a short vagina and an absent cervix and uterus