കാലി acids are cleared incompletely and accumulate in plasma but the cause is unclear
B:-pruritus shows predilection for the soles and may precede laboratory findings by several weeks
total plasma concentrations of bilirubin exceed 8 mg/dl and serum transaminases exceed 500 in 30% patients
D-ursodeoxycholic acid relieves pruritus and improves fetal outcome better than steroids and cholestyramine
Correct Answer:- Option-C
Question91:-All the statements about sickle cell anaemia in pregnancy are TRUE EXCEPT
‘AcSickle-cell trait does not appear to be associated with increased perinatal mortality, low birthweight or pregnancy-induced hypertension
Bsn Sickle cell disease there is no categorical contraindication to vaginal delivery, and caesarean delivery is reserved for obstetrical indications
C=Routine prophylactic blood transfusions during labour is recommended to reduce painful crises in Sickle cell anaemia
D:-Antenatal folic acid supplementation with 4 mg daily throughout pregnancy is needed to support rapid red blood cell turnover
Correct Answer:- Option-C
Question92:-All the statements about thrombocytopenia in pregnancy are TRUE EXCEPT
‘AA platelet count of < 80,000/L should trigger an evaluation for etiologies other than gestational thrombocytopenia
B:-Hypertensive disorders account for 21% of thrombocytopenia in pregnancy
Cin ITP complicating pregnancy, therapy with steroids is considered if the platelet count is below 30,000 to 50,000/L
D-Maternal platelet counts have strong correlation with fetal platelet counts and caesarean delivery is recommended if platelet count is < 50,000 on fetal blood sampling
Correct Answer:- Option-D
Question93:-All the following statements regarding diabetes in pregnancy are TRUE EXCEPT
‘A: Periconceptional HBALC should be kept under 6.5% in pregestational diabetic women
B:-MSAFP levels may be lower in diabetic pregnancies and the incidence of congenital cardiac anomalies is five fold in mothers with diabetes
C-Ultra short acting insulin analogues starts acting in 30 minutes, peaks in 2 hrs minutes and is good for preprandial glycemic control in pregnancy
D-Insulin therapy is typically added if fasting levels persistently exceed 95 mg/dl after medical nutrition therapy
Correct Answer:- Option-C
Question94:-All the statements about thyroid in pregnancy are TRUE EXCEPT
‘A: Women with TPO antibodies are at increased risk for progression of thyroid disease and postpartum thyroiditis
Belt is recommended that women avoid pregnancy for 1 month after radioablative therapy with iodine 131
Pregnancy is associated with an increased thyroxine requirement in approximately a third of supplemented women
D:-Prophylthiouracil (PTU) is preferred in pregnancy because it partially inhibits the conversion of T4 to T and crosses the placenta less readily than methimazole
Correct Answer:- Option ®
Question95:-All the statements about SLE in pregnancy are TRUE EXCEPT
‘Ac Fetal cell micro chimerism leads to the predilection for autoimmune disorders like SLE among women
Bsn the presence of anti-Ro and Ant-La antibodies, the incidence of fetal myocarditis and heart block is as high as 20%
C:During pregnancy, lupus improves in a third of women, remains unchanged in a third and worsens in the remaining third
D:-Hydroxychloroquine is not associated with congenital malformations and can be continued in pregnancy
Correct Answer:- Option ®
Question96:-All are TRUE about antiphospholipid antibody syndrome EXCEPT
[AcAsherson syndrome is a rapidly progressive thromboembolic disorder due to a cytokine storm seen in antiphospalipid antibody syndrome
B:-Approximately 60 percent of patients with APS have a positive lupus anticoagulant LAC assay alone
C:Heparin binds to beta 2 glycoprotein | and prevents binding of anticardiolipin andarti-beta 2 glycoprotein | antibodies to the syncytiotrophoblasts
D-Treatment using aspirin, anticoagulation and close monitoring has increased live birth rates to more than 70 percent in women with APS
Correct Answer:- Option ®
Question97:-All are TRUE about management of obstetric haemorrhage EXCEPT
‘AcThe most important mechanism of action with internal iiac artery ligation is an 85-percent reduction in pulse pressure in those arteries distal to the ligation
B:-ROTEM or TEG cannot diagnose coagulopathies stemming from platelet dysfunction or anti platelet drugs
C:Each single-donor apheresis six-unit bag raises the platelet count by approximately 5000/L.
D:-Dilutional coagulopathy that is clinically indistinguishable from DIC is the most frequent coagulation defect found with blood loss and multiple transfusions
Correct Answer:- Option-C
Question98:-All are TRUE about USS features of Placenta Accreta Spectrum (PAS) EXCEPT
‘Acloss of the normal hypoechoicretroplacentalzone between the placenta and uterus

Beplacental vascular lacunae or lakes