FINAL ANSWER KEY

Question Paper വാട: 4/2021/0L
Category Code: 012/2020

Exam: Assistant Professor in Nephrology
Date of Test 08-03-2021

Department Medical Education Services
Alphacode A

Questionz:-Which of the following statement about transplant immunosuppressive drugs is NOT TRUE ?
‘AsCyclosporin binds to FK 506 binding protein in the cytoplasm and inhibits calcineurin
B:Tacrolimus is 2 macrolide antibiotic
C-Mycophenolate mofetil acts by inhibiting Inosine Monophosphate dehydrogenase
D:-Sirolimus shares its cytoplasmic binding protein with Tacrolimus (FBP12)
Correct Answer:- Option-é
Question2::Which one of the following is an inhibitor of vascular calcification in CKD ?
‘Ac Protein 5
B:-Klotho
CMatrix metallprotein
D:-Fetuina
Correct Answer:- Option-D
Question3:-Erythrocytosis in patients with CKD is seen in all ofthe following conditions EXCEPT
‘Ac Polycystic kidney disease
B:-Chronic allograft Nephropathy
CeRenal artery stenosis
Renal tumours
Correct Answer:- Option ®
Questioné::Which of the following statement IS TRUE regarding FGF 23 a key regulator in bone and mineral metabolism in CKD ?
‘Aclts chief action is to reduce phosphate reabsorption in the proximal tubule
B:-FGF 23 retards the progression of CKD in diabetics and non-diabetics
Increased phosphate excretion is the stimuli for increase FGF 23 production
D-FGF 23 protects against the development of hyperparathyroidism
Correct Answer:- Option-é
QuestionS:-Al ofthe following are side effects of Carbonic anhydrase inhibitor (acetazolamide) use, EXCEPT
‘AcIncrease the risk of nephrolithiasis
B:-Precipitate encephalopathy in patients with liver failure
CzSymptomatic metabolic alkalosis
D-Decreased libido
Correct Answer:- Option-C
Question6::Which of the following drug combinations is considered unacceptable or ineffective in treating Hypertension ?
‘AcBeta-blockers and central adrenergic agents (eg. clonidine)
B:-Calcium chamnel blockers and thiazide diuretics
C=Caleium channel blockers and Beta-blockers
D-RAAS blockers and Calcium channel blockers
Correct Answer:- Option-é
Question7:-Identify the INCORRECT statement about the biomarkers in pre-eclampsia,
‘A: Placental Protein 13 (PP13) is involved in normal placentation
B:-sFItL level is increased in severe pre-eclampsia
C-sFitl to PIGF (Placental Growth Factor) ratio can be used in risk stratification in women with suspected pre-eclampsia
D-Urinary levels of PIGF are sigrificantly higher in women who develop pre-eclampsia

Correct Answer: Option-D