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Below are the scanned copy of Kerala Public Service Commission (KPSC) Question Paper with answer keys of Exam Name 'Research Officer- Chemistry/ Biochemistry' And exam conducted in the year 2023. And Question paper code was '027/2023/OL'. Medium of question paper was in Malayalam or English . Booklet Alphacode was ''. Answer keys are given at the bottom, but we suggest you to try answering the questions yourself and compare the key along wih to check your performance. Because we would like you to do and practice by yourself.
C:-The dose at which 50% of the tested animals exhibit a biological response
D:-The dose at which some animals exhibit a biological response
Correct Answer:- Option-C
Question37:-Match the following drugs with their General targets
Drugs General Targets
^. Rifampicin 1. Act on 30S subunit of ribosome and block the
protein
synthesis
B. Tetracycline ii. Binds to RNA polymerase and interferes
transcription
process
C. Cephalosporins iii. Act on 50S subunit of ribosome and block the
protein
synthesis
D. Erythromycin iv. Inhibit the cell wall synthesis
A:-A-iv, B-ii, C-i, D-iii
B:-A-ii, B-i, C-iv, D-iii
C:-A-ii, B-iii, C-iv, D-i
D:-A-iii, B-iv, C-i, D-ii
Correct Answer:- Option-B
Question38:-Which of the following statement about Cytochrome P450 is false?
A:-Cytochrome P450 (CYP) is a hemeprotein that plays an important role in
drug and xenobiotic metabolism
B:-A fat-free diet increases the Cytochrome P450 level
C:-Phase | reactions of drug metabolism are mainly catalyzed by the
Cytochrome P450
D:-Cytochrome P450 belongs to the class of enzymes called monooxygenase
Correct Answer:- Option-B
Question39:-Which of the following reaction doesn't involve phase II of drug
metabolism
A:-Glucuronidation
B:-Sulfaction
C:-Methylation
D:-Hydroxylation
Correct Answer:- Option-D
Question40:-Match the bacterial toxins with their mode of action
Toxins Mode of action
^. Pertussis toxin i. Inhibit neurotransmitter release in a neuron
B. Diphtheria toxin ii. Selective blockers of acetylcholine release
from nerve
endings
C. Botulinum toxin iii. Inactivates elongation factor (EF-2) and
inhibits