Question58:-FDA approved antiangiogenic drug Regorafenib improves overall survival in chemo refractory metastatic
colorectal cancer is

A:-1.4 months
.7 months
C:-6.2 months
D:-8.1 months
Correct Answer:- Option-A
Question59:-Which of the following is not a Hallmark of cancer ?
A:-Self-sufficiency in growth signals
B:-Sensitivity to anti-growth signals
C:-Resistance to Apoptosis
D:-Limitless replicative potential
Correct Answer:- Option-B
Question60:-Which is wrong regarding hyper fractonation ?
A:-Smaller than standard doses/fraction
B:-Treating once a day for 6 or 7 days/week
C:-Usually gives two fractions/day for five days/week
D:-Overall treatment time prolonged
Correct Answer:- Option-D
Question61:-Van Nuys Prognostic Index for ductal carcinoma in (breast) considers following features except
A:-Lesion size
B:-Perivascular invasion
:-Margins
D:-Histology
Correct Answer:- Option-B
Question62:-Positive immunohistochemistry staining for calcitonin in medullary carcinoma thyroid has sensitivity range of
in cytology specimen
-95-100%
-75-80%
C:-65-70%
D:-55-60%
Correct Answer:- Option-D

Question63:-For detecting Minimal residual disease following complete clinical remission in leukemia, which test technique
helps in decreasing false positives

A:-Polymerase Chain Reaction (PCR)
B:-Reverse transcriptase PCR
C:-Real time PCR
D:-Florescent In situ Hybridization
Correct Answer:- Option-C
Question64:-Which chromosomal translocation in ALL have favorable prognosis ?
A:-t(12;21) (p12;q22)
B:-t(9;22) (q34;q11)
C:-t(1;19) (q23;p13)
D:-t(4;11) (q21:q23)
Correct Answer:- Option-A
Question65:-The following gene expression profiles in Diffuse Large B cell Lymphoma shows poor prognosis except
A:-Bcl-2 expression
B:-Bcl-1 expression
C:-HLA-DR expression
D:-P53 gene mutation
Correct Answer:- Option-B
Question66:-True regarding flow cytometry in cancer diagnosis include
A:-Prompt result availability
B:-Need for fresh specimen
C:-Can analyze two or more markers simultaneously
D:-All of the above
Correct Answer:- Option-D
Question67:-T4N2M1 (ipsilateral) carcinoma lung comes under which composite stage ?
A:-Stage IIB
B:-Stage IIIA